Publications

27. Saskemycin, a potent and selective antimycobacterial agent targeting a unique site on the ribosome

Michael Cook, Min Xu, Martino Morici, Dmitrii Travin, Wenliang Wang, Dorota Klepacki, Nandini Chhabra, Vishwas Rao, Henok Sahile, Dirk Hackenberger, Haaris Safdari, Max Berger, Martina Corazza, Austin Bond, Allison Guitor, Dominique Tertigas, Lijun Wang, Adam Schaenzer, Linda Ejim, Venkateswarlu Yarlagadda, James Gomez, Michael Surette, Yossef Av-Gay, Neeraj Dhar, Deborah Hung, Nora Vázquez-Laslop, Alexander Mankin, Daniel Wilson, Gerard Wright

Manuscript under Review

26. π-Conjugated Porous Polymer Nanosheets for Explosive Sensing: Investigation on the Role of H-Bonding

Saurabh Kumar Rajput, Atul Kapoor, Abhishek Yogi, Venkateswarlu Yarlagadda, Suresh Mothika

Chemistry: An Asian Journal, 2024, 19, e202400939

25. Exploring the Darobactin Class of Antibiotics: A Comprehensive Review from Discovery to Recent Advancements

Akash Dutta, Peehu Sharma, Dharam Dass, Venkatewarlu Yarlagadda*

ACS Infectious Diseases, 2024, 10, 8, 2584–2599

24. A screen of natural product extracts identifies moenomycin as a potent antigonococcal agent

V. Yarlagadda, V. N. Rao, M. Kaur, A. Guitor, G. D. Wright

ACS Infectious Diseases, 2021, 7, 1569-1577.

23. Resistance-guided discovery of elfamycin antibiotic producers with antigonococcal activity

V. Yarlagadda, R. Medina, T. Johnson, G. Cox, K. Koteva, M. N. Thaker, G. D. Wright

ACS Infectious Diseases, 2020, 6, 12, 3163–3173.

22. Venturicidin, a membrane-active natural product inhibitor of ATP synthase potentiates aminoglycosides antibiotics

V. Yarlagadda, R. Medina, G. D. Wright

Scientific Reports, 2020, 10, 8134.

21. Vancomycin derivative inactivates carbapenem-resistant Acinetobacter baumannii and induces autophagy

P. Sarkar, S. Samaddar, V. Ammanathan, V. Yarlagadda, C. Ghosh, M. Shukla, G. Kaul, R. Manjithaya, S. Chopra, J. Haldar

ACS Chemical Biology, 2020, 15, 884-889.

20. Membrane-active rhamnolipids overcome aminoglycoside resistance

V. Yarlagadda, G. D. Wright

Cell Chemical Biology, 2019, 26, 1333-1334.

19. Vancomycin analogue restores meropenem activity against NDM-1 Gram-negative pathogens

V. Yarlagadda, P. Sarkar, S. Samaddar, G. B. Manjunath, S. D. Mitra, K. Paramanandham, B. R. Shome, J. Haldar

ACS Infectious Diseases 2018, 4, 1093-1101.

18. A vancomycin derivative with a pyrophosphate-binding group: A strategy to combat vancomycin-resistant bacteria. (Highlighted as a "Very important paper" in antibiotics)

V. Yarlagadda, P. Sarkar, S. Samaddar, J. Haldar

Angewandte Chemie International Edition, 2016, 27, 7836-7840.

17. A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics

P. Sarkar, V. Yarlagadda, C. Ghosh, J. Haldar

MedChemComm, 2017, 8, 516-533.

16. Glycopeptide antibiotic to overcome the intrinsic resistance of Gram-negative bacteria

V. Yarlagadda, G. B. Manjunath, P. Sarkar, P. Akkapeddi, K. Paramanandham, S. B. Ranjan, R. Ravikumar, J. Haldar

ACS Infectious Diseases 2016, 2, 132-139.

15. Lipophilic vancomycin aglycon dimer with high activity against vancomycin-resistant bacteria

(Highlighted in Nature India "New defence against superbugs")

http://www.natureasia.com/en/nindia/article/10.1038/nindia.2015.151

V. Yarlagadda, P. Sarkar, G. B. Manjunath, J. Haldar

Bioorganic & Medicinal Chemistry Letters, 2015, 25, 5477-5480.

14. Intracellular activity of membrane active glycopeptide antibiotic (YV11455) against MRSA infection

V. Yarlagadda, S. Samaddar, J. Haldar

Journal of Global Antimicrobial Resistance, 2016, 5, 71-74.

13. Membrane disruption and enhanced inhibition of cell-wall biosynthesis: A synergistic approach to tackle vancomycin-resistant bacteria. (Highlighted as a "Hot paper" in drug design).

V. Yarlagadda, S. Samaddar, K. Paramanandham, B. R. Shome, J. Haldar

Angewandte Chemie International Edition 2015, 54, 13644-13649.

12. Membrane active small molecules show selective broad spectrum antibacterial activity with no detectable resistance and eradicates biofilms bacteria

J. Hoque, M. M. Konai, S. Gonuguntla, G. B. Manjunath, Sandip Samaddar, V. Yarlagadda, J. Haldar

Journal of Medicinal Chemistry, 2015, 58, 5486-5500.

11. In-vivo efficacy and pharmacological properties of a novel glycopeptide (YV4465) against vancomycin-intermediate Staphylococcus aureus

V. Yarlagadda, M. M. Konai, K. Paramanandham, V. C. Nimitha, B. R. Shome, J. Haldar

International Journal of Antimicrobial Agents, 2015, 46, 446-450.

10. Broad spectrum antibacterial and antifungal polymeric paint materials: Synthesis, structure-activity relationship, and membrane-active mode of action

J. Hoque, P. Akkapeddi, V. Yadav, G. B. Manjunath, D. S. S. M. Uppu, M. M. Konai, V. Yarlagadda, K. Sanyal, J. Haldar

ACS Applied Materials & Interfaces, 2015, 7, 1804-1815.

9. Membrane-active macromolecules resensitize NDM-1 Gram-negative clinical isolates to tetracycline antibiotics

D. S. S. M. Uppu, G. B. Manjunath, V. Yarlagadda, J. E. Kaviyil, R. Ravikumar, K. Paramanandham, B. R. Shome, J. Haldar

PLoS ONE, 2015, 10, e0119422.

8. In-vivo antibacterial activity and pharmacological properties of the membrane-active glycopeptide antibiotic YV11455

V. Yarlagadda, M. M. Konai, G. B. Manjunath, R. G. Prakash, B. Mani, K. Paramanandham, S. B. Ranjan, R. Ravikumar, S. P. Chakraborty, S. Roy, J. Haldar

International Journal of Antimicrobial Agents, 2015, 45, 627-634.

7. Tackling vancomycin-resistant bacteria with 'lipophilic-vancomycin-carbohydrate conjugates'.

V. Yarlagadda, M. M. Konai, G. B. Manjunath, C. Gosh, J. Haldar

The Journal of Antibiotics, 2015, 68, 302-312.

6. Membrane active phenylalanine conjugated lipophilic norspermidine derivatives with selective antibacterial activity

M. M. Konai, C. Ghosh, V. Yarlagadda, S. Samaddar, J. Haldar

Journal of Medicinal Chemistry, 2014, 57, 9409-9423.

5. Effect of amide bonds on the self-assembly of Gemini surfactants

J. Hoque, S. Gonuguntla, V. Yarlagadda, V. K. Aswal, J. Haldar

Physical Chemistry Chemical Physics, 2014, 16, 11279-11288.

4. Small molecular antibacterial peptoid mimics: The simpler the better!

C. Ghosh, G. B. Manjunath, P. Akkapeddi, V. Yarlagadda, J. Hoque, D. S. S. M. Uppu, M. M. Konai, J. Haldar